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Duodopa Treatment
 

Introduction

Treatment involves an operation to make a small opening in the abdomen so that a tube can be passed into the bowel. The tube is then connected to a portable pump that is worn during the day and feeds levodopa/carbidopa directly into the bowel. This means that the medication bypasses the stomach, where most of the levodopa absorption problems occur, and therefore has a better chance of controlling symptoms. The pump is disconnected at bedtime but tablets are available to manage troublesome night-time symptoms if needed.

Treatment Plan

Click Here to download Duodopa Treatment Plan

Test Treatment

In order to test Duodopa, a nasointestinal tube is used for a test period of approximately 3-5 days. The nasointestinal tube is inserted with the help of x-ray or gastroscope.


Advantages of using the nasointestinal tube

  • Does not need an operation
  • Medication can be discontinued if the treatment is not suitable

During the test period, the continual infusion dose of Duodopa will be closely monitored by the Solvay Nurse and the ward staff.

The rate at which Duodopa is infused will be calculated from the patient's initial dose of oral medication before admission. This will be changed throughout the test period according to the severity of symptoms.

This will be continually assessed until the patient has reached their best therapy treatment, which can take anything from 3-5 days in the hospital.

Permanent Treatment

After the test period has been completed, it will then be decided by the patient and the Neurologist whether to continue with permanent Duodopa therapy.

This will involve a tube (PEG) being inserted into the patient’s stomach with the help of a gastroscope (a thin, lighted tube used to view the inside of the stomach) whilst under light sedation/local anaesthesia.

An 'inner tube' is put through the tube (PEG) and pushed through the pylorus (the muscular valve separating the stomach from the small intestine). Treatment will continue once the PEG has been inserted.

The wound site surrounding the PEG tube will require a dressing initially but will heal and need just regular cleaning with soap and water and thorough drying (further information can be found in the Patient Information booklet).

The treatment will then continue via the PEG and pump.

The patient will be discharged once all arrangements have been made and both the patient and carer feel completely confident and competent in using the Duodopa therapy pump system.

 

Use of Duodopa following PEG Surgery

Click here to view and download a wallchart on your daily routine following PEG surgery.

Once Home

Home Care Delivery

All supplies needed for the Duodopa therapy are provided by a home delivery service, Healthcare at Home.

They will supply on a monthly basis the Duodopa cassettes (which require refrigeration until they are used) and all other equipment required.

Once the patient has been referred for Duodopa treatment, Healthcare at Home (with the patient's consent) will be informed of the date therapy is to commence and the discharge home date. They will contact the patient to arrange a suitable date for the medication and equipment to be delivered to their home address.

Throughout treatment, a Solvay Nurse Advisor will be able to liaise between the patient and Healthcare at Home if any problems are experienced with deliveries.

Contact telephone number for Healthcare at Home:
0870 600 1542
Contact telephone number for the Solvay Nurse Advisor 24 hr Helpline:
0800 458 4410



 

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